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is in a group of drugs called proton pump inhibitors. Rabeprazole decreases the amount of acid produced in the stomach. Rabeprazole is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome

Rabeprazole is used to treat certain conditions where there is too much acid in the stomach. It is used to treat duodenal ulcers and gastroesophageal reflux disease (GERD), a condition where the acid in the stomach washes back up into the esophagus. Sometimes rabeprazole is used along with antibiotics (e.g., amoxicillin, clarithromycin) to treat ulcers associated with infections caused by the H. pylori bacteria.

Rabeprazole is also used to treat Zollinger-Ellison syndrome, a condition in which the stomach produces too much acid.

Rabeprazole is a proton pump inhibitor (PPI). It works by decreasing the amount of acid produced by the stomach..
Safety and efficacy have not been established..
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of rabeprazole in the elderly.
  Pregnancy Category Explanation
All Trimesters B Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.
Breast Feeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Using rabeprazole with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Atazanavir
• Clopidogrel
• Dasatinib
• Erlotinib
• Mycophenolate Mofetil
• Nelfinavir
• Nilotinib
Using rabeprazole with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Cranberry
• Digoxin
• Itraconazole
• Ketoconazole
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of rabeprazole. Make sure you tell your doctor if you have any other medical problems, especially:

• Hypomagnesemia (low magnesium in the blood), history of or
• Osteoporosis (bone problem) or
• Stomach infection (e.g., pseudomembranous colitis)—Use with caution. May make these conditions worse.
• Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.
Uses For domperidone

Domperidone is a medicine that increases the movements or contractions of the stomach and bowel. Domperidone is also used to treat nausea and vomiting caused by other drugs used to treat Parkinson's Disease.
Children—Studies on domperidone have been done only in adult patients, and there is no specific information comparing use of domperidone in children.
There is no specific information comparing the use of domperidone in the elderly with use in other age groups.
Breast Feeding
Studies suggest that this medication may alter milk production or composition. If an alternative to this medication is not prescribed, you should monitor the infant for side effects and adequate milk intake.
Other Medical Problems:
• Bleeding from the stomach or other problems involving the bowels
• Pituitary (brain) tumor
• Liver disease
• Medicine sensitivity to domperidone
Precautions While Using domperidone
It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it.
If your symptoms do not improve within a few days or if they become worse, check with your doctor.

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